Doç Dr. Meral Günaldı - Neolife Tıp Merkezi
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Doç Dr. Meral Günaldı

Doç Dr. Meral Günaldı

Medikal Onkoloji ve iç Hastalıkları Uzmanı

Eğitim

2015 –  Halen    İstanbula Üniversitesi – Deneysel Tıp Araştırma Enstitüsü / İmmünoloji Anabilim Dalı

2009 – 2012    Çukurova Üniversitesi – Tıp Fakültesi /TIP PR.tıbbi onkoloj / Lisans

2004 – 2009    Tıpta Uzmanlık / Doktora Tez adı: Kan selenyum düzeyi ve glutatyon peroksidaz aktivitesinin akut miyokart enfarktüsü üzerine etkisi (2009) Tez Danışmanı:(Ayşen Helvacı)

1994 – 2001    Karadeniz Teknik Üniversitesi – Tıp Fakültesi – Lisans / Yüksek Lisans

İş Deneyimi

2016 – Halen   Neolife Tıp Merkezi

2013 – 2016     İstanbul Bakırköy Dr. Sadi̇ Konuk Eğitim Araştırma Hastanesi / Uzman

2009 – 2012       Çukurova Üni̇versi̇tesi̇/tip Fakültesi̇/dahi̇li̇ Tip Bi̇li̇mleri̇ Bölümü/i̇ç Hastaliklari Anabi̇li̇m Dali / Araştırma Görevlisi

2004 – 2009       İstnbul Okmeydanı Eğitim ve Araştırma Hastanesi / Araştırma Görevlisi

Üyelikler

  • Türk Nöroonkoloji Derneği, Üye  , 2014
  • Europian Society of Medical Oncology, Üye  , 2011
  • Tıbbi Onkoloji Derneği, Üye  , 2010

Bilimsel Çalışmalar

A1) Acute myocardial infarction in a patient with hemophilia A and factor V Leiden mutation. Günaldi M, Helvaci A, Yildirim ND, Kiskaç M, Küçükkaya RD. Cardiol J. 2009;16(5):458-61.
A2) Primary cutaneous small-cell carcinoma: a case report. Duman BB, Kara IO, Günaldi M, Erçolak V. Med Oncol. 2011 Dec;28 Suppl 1:S634-5. doi: 10.1007/s12032-010-9672-3. Review
A3) Malignant mixed Mullerian tumor of the ovary with two cases and review of the literature. Duman BB, Kara IO, Günaldi M, Ercolak V. Arch Gynecol Obstet. 2011 Jun;283(6):1363-8. doi: 10.1007/s00404-011-1845-6. Review.
A4) Multiple myeloma with serous membrane involvement and increased CA-125 and CA 15-3. Gunaldi M, Helvaci A, Demirel Yildirim N, Aydin D, Kara N. J BUON. 2011 Oct-Dec;16(4):778.
A5) Hodgkin’s lymphoma of the surrenal: case report and review of the literature Gunaldi M, Paydaş S, Ercolak V, Duman B, Ergin M. Open Journal of oncology 2011:1-1
A6) Alteration in serum levels of selenium and glutathione peroxidase in acute myocardialinfarction Gunaldi M, Helvaci A, Zorlu M, Kiskac M, Ekmen N, Yilmaz G. Oxid Antioxid Med Sci. 2012; 1(3): 175-178
A7) Primary intrapulmonary thymoma associated with myasthenia gravis. Günaldi M, Oguz Kara I, Duman BB, Gumurdulu D.
Gen Thorac Cardiovasc Surg. 2012 Sep;60(9):610-3. doi: 10.1007/s11748-012-0064-9.
A8) Capecitabine-induced hypertriglyceridemia and hyperglycemia: two cases. Duman BB, Paydas S, Tetiker T, Gunaldı M, Afsar CU, Erçolak V, Haksöyler V, Dilli MŞ.
Pharmacology. 2012;90(3-4):212-5. doi: 10.1159/000342382. Review
A9) Retrospective analysis of neoadjuvant chemotherapy for breast cancer in Turkish patients. Duman BB, Afşar ÇU, Günaldi M, Sahin B, Kara IO, Erkisi M, Erçolak V.
Asian Pac J Cancer Prev. 2012;13(8):4119-23.
A10) Retrospective analysis of 498 primary soft tissue sarcomas in a single Turkish centre. Duman BB, Gunaldi M, Ercolak V, Afsar CU, Sahin B, Erkisi IM, Kara O, Paydas S, Gönlüsen G, Sertdemir Y. Asian Pac J Cancer Prev. 2012;13(8):4125-8.
A11) Primary intracerebral myeloid sarcoma. Gunaldi M, Kara IO, Duman BB, Ercolak V.
Onkologie. 2012;35(11):694-7. doi: 10.1159/000343953.
A12) Coexistence of tuberous sclerosis complex and malignant melanoma. Günaldi M, Paydas S, Afsar CU, Doran F. Singapore Med J. 2013;54(11):e233-5.
A13) Carbamazepine and Multiple Myeloma: Possible Interaction Gunaldı M, Paydaş S, Afşar CU, Duman BB, Ercolak V, Haksoyler V. Turk J Haematol. 2013;30(1):83-4. doi: 10.4274/tjh.2012.0153.
A14) Sweet syndrome in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma: curious lymphocyte/neutrophil fluctuations. Usul Afşar C, Paydaş S, Günaldı M, Bozkurt Duman B, Erçolak V, Zorludemir S, Açıkalın A. Turk J Haematol. 2013;30(4):413-5. doi: 10.4274/Tjh.2012.0055
A15) A New Approach to the Treatment of Metastatic Paraganglioma: Sorafenib. Gunaldi M, Kara IO, Duman BB, Afsar CU, Ergin M, Avci A. Cancer Res Treat. 2014 doi: 10.4143/crt.2013.093.
A16) Bilateral primary adrenal non-hodgkin lymphoma. Erçolak V, Kara O, Günaldı M, Usul Afşar C, Bozkurt Duman B, Açıkalın A, Ergin M, Erdoğan S. Turk J Haematol. 2014 ;31(2):205-6. doi: 10.4274/tjh.2013.0195.
A17) Diagnostic and prognostic roles of DOG1 and Ki-67, in GIST patients with localized or advanced/metastatic disease. Sözütek D, Yanık S, Akkoca AN, Sözütek A, Ozdemir ZT, Avşar CU, Günaldı M, Sahin B, Doron F. Int J Clin Exp Med. 2014;7(7):1914-22.
A18) Abdominal actinomycosis with multiple myeloma: A case report. Ercolak V, Paydas S, Ergin M, Ates BT, Duman BB, Gunaldi M, Afsar CU. Oncol Lett. 2014:1876-1878.
A19) A case report of adult Wilms’Tumour. Ercolak V, Kara IO, Duman BB, Günaldı M, Afşar CU, Erdoğan S, Ateş BA. Contemp Oncol (Pozn) 2014; 18 DOI: 10.5114/wo.2014.40616
A20) Measurement of the knowledge level about breast self-exam among the female employees of a university hospital, Turkey Sişman H, Ozgen R, Baysal D, Sarιakçalι N, Ozturk S, Kum P, Gurel D, Kanarιģ D, Aslaner E, Akιl Y, Meral Günaldι Asia Pac J Oncol Nurs 2014;1(1):40
A21) Intra-Ventricular Tumors: Assessment of 40 Cases Postalcı LS, Günaldı O, Demirgil B, Baydın S, Tuğcu B, Günaldı M. Ofluoğlu E. OJMN 2014: Vol.4 No.2 DOI: 10.4236/ojmn.2014.42012
A22) Evaluation of CYP2D6 Polymorphic Types and Their Effect on Tamoxifen Efficacy Among Turkish Tamoxifen Users with Breast Cancer. Günaldı M, Erkisi M, Afşar CU, Ercolak V, Duman BB, Paydas S, Kara IO, Berksoy SAHIN, Tuli A, Secilmis A. International Journal of Hematology and Oncology 2014 Number: 3 Volume: 24
A23) Evaluation of Endometrial Thickness and Bone Mineral Density Based on CYP2D6 Polymorphisms in Turkish Breast Cancer Patients Receiving Tamoxifen Treatment Gunaldi M et al. Pharmacology DOI: 10.1159/000363304
A24) Paraoxonase-1 and arylesterase activities in patients with colorectal cancer. Afsar CU, Gunaldı M, Okuturlar Y, Gedikbası A, Tiken EE, Kahraman S, Karaca F, Ercolak V, Karabulut M. Int J Clin Exp Med. 2015 Nov 15;8(11):21599-604.
A25) Heat shock protein 70 is a useful marker for predicting colorectal cancer. Gunaldi M, Kocoglu H, Okuturlar Y, Gedikbasi A, Karabulut M, Alis H, Hursitoglu M. J BUON. 2015 Nov-Dec;20(6):1464-70.
A26) Clinical significance of serum claudin-1 and claudin-7 levels in patients with colorectal cancer. Karabulut M, Alis H, Bas K, Karabulut S, Afsar CU, Oguz H, Gunaldi M, Akarsu C, Kones O, Aykan NF. Mol Clin Oncol. 2015 Nov;3(6):1255-1267. Epub 2015 Aug 31.
A27) Diagnostic importance of S100A9 and S100A12 in breast cancer. Gunaldi M, Okuturlar Y, Gedikbasi A, Akarsu C, Karabulut M, Kural A. Biomed Pharmacother. 2015 Dec;76:52-6. doi: 10.1016/j.biopha.2015.10.029. Epub 2015 Nov 10.
A28) Expression of fibroblast growth factor receptor 1, fibroblast growth factor 2, phosphatidyl inositol 3 phosphate kinase and their clinical and prognostic significance in early and advanced stage of squamous cell carcinoma of the lung. Usul Afsar C, Sahin B, Gunaldi M, Kılıc Bagir E, Gumurdulu D, Burgut R, Erkisi M, Kara IO, Paydas S, Karaca F, Ercolak V. Int J Clin Exp Pathol. 2015 Sep 1;8(9):9760-71.
A29) Efficacy of paclitaxel in the treatment of Kaposi sarcoma. Ercolak V, Sahin B, Gunaldi M, Duman BB, Afsar CU. Eur Rev Med Pharmacol Sci. 2015 Nov;19(21):4095-100.
A30) Serum galactomannan levels in the diagnosis of invasive aspergillosis. Okuturlar Y, Ozkalemkas F, Ener B, Serin SO, Kazak E, Ozcelik T, Ozkocaman V, Ozkan HA, Akalin H, Gunaldi M, Ali R. Korean J Intern Med. 2015 Nov;30(6):899-905. doi: 10.3904/kjim.2015.30.6.899.
A31) The Cost-Effectiveness Of Regorafenib In The Treatment Of Patients With Metastatic Colorectal Cancer (Mcrc) Who Have Progressed After Standard Therapies In Turkey. Deger C, Telli F, Gunaldi M, Keskin S, Saglam S, Ozdemir O, Sar C, Parali E, Erdal E, Sumer F, Ozel O, Asan S. Value Health. 2015 Nov;18(7):A458. doi: 10.1016/j.jval.2015.09.1176. Epub 2015 Oct 20.
A32) The Cost-Effectiveness Of Regorafenib In The Treatment Of Metastatic/Inoperable Gastrointestinal Stromal Tumors In Turkey. Deger C, Telli F, Gunaldi M, Keskin S, Saglam S, Ozdemir O, Sar C, Parali E, Erdal E, Sumer F, Ozel O, Asan S. Value Health. 2015 Nov;18(7):A455. doi: 10.1016/j.jval.2015.09.1161. Epub 2015 Oct 20.
A33) The Cost-of-Disease of Metastatic/Inoperable Gastrointestnal Stromal Tumors in Turkey: an Expert Panel Approach for Estimation of Costs. Deger C, Telli F, Gunaldi M, Keskin S, Saglam S, Ozdemir O, Sar C, Parali E, Erdal E, Sumer F, Ozel O, Asan S. Value Health. 2015 Nov;18(7):A449. doi: 10.1016/j.jval.2015.09.1130. Epub 2015 Oct 20.
A34) The Life Time Cost-of-Disease (Cod) of Metastatic Colorectal Cancer (Mcrc) in Turkey: an Expert Panel Approach for Estimation of Costs. Deger C, Telli F, Gunaldi M, Keskin S, Saglam S, Ozdemir O, Sar C, Parali E, Erdal E, Sumer F, Ozel O, Asan S. Value Health. 2015 Nov;18(7):A448. doi: 10.1016/j.jval.2015.09.1124. Epub 2015 Oct 20. No abstract available.
A35) Serum nectin-2 levels are diagnostic and prognostic in patients with colorectal carcinoma. Karabulut M, Gunaldi M, Alis H, Afsar CU, Karabulut S, Serilmez M, Akarsu C, Seyit H, Aykan NF. Clin Transl Oncol. 2016 Feb;18(2):160-71. doi: 10.1007/s12094-015-1348-1.
A36) Effect of the cumulative dose of zoledronic acid on the pathogenesis of osteonecrosis of the jaws. Gunaldi M, Afsar CU, Duman BB, Kara IO, Tatli U, Sahin B. Oncol Lett. 2015 Jul;10(1):439-442.
A37) Prognostic impact of platelet/lymphocyte and neutrophil/lymphocyte ratios in patients with gastric cancer: a multicenter study. Gunaldi M, Goksu S, Erdem D, Gunduz S, Okuturlar Y, Tiken E, Kahraman S, Inan YO, Genc TB, Yildirim M. Int J Clin Exp Med. 2015 Apr 15;8(4):5937-42.
A38) PRAME Expression and Its Clinical Relevance in Hodgkin’s Lymphoma. Ercolak V, Paydas S, Bagir E, Ergin M, Seydaoglu G, Celik H, Yavu B, Tanriverdi K, Gunaldi M, Afsar CU, Duman BB. Acta Haematol. 2015;134(4):199-207.
A39) Elevated serum levels of heat shock protein 70 are associated with breast cancer.
Gunaldi M, Afsar CU, Okuturlar Y, Gedikbasi A, Kocoglu H, Kural A, Akarsu C, Gunduz U, Tiken EE. Tohoku J Exp Med. 2015;236(2):97-102. doi: 10.1620/tjem.236.97.
A40) Utility of peripheral blood parameters in predicting breast cancer risk. Okuturlar Y, Gunaldi M, Tiken EE, Oztosun B, Inan YO, Ercan T, Tuna S, Kaya AO, Harmankaya O, Kumbasar A. Asian Pac J Cancer Prev. 2015;16(6):2409-12.
A41) Alterations of ghrelin with weights and correlation among ghrelin, cytokine and survival in patients receiving chemoradiotherapy for gastrointestinal cancers. Karaca F, Afsar CU, Gunaldi M, Erkurt E, Ercolak V, Sertdemir Y, Paydas S. Int J Clin Exp Med. 2015 Jan 15;8(1):876-82.
A42) Risk factors for developing cardiotoxicity of trastuzumab in breast cancer patients: An observational single-centre study. Gunaldi M, Duman BB, Afsar CU, Paydas S, Erkisi M, Kara IO, Sahin B. J Oncol Pharm Pract. 2016 Apr;22(2):242-7. doi: 10.1177/1078155214567162. Epub 2015 Jan 7.
A43) Pancreatic carcinoma, thrombosis and mean platelet volume: single center experience from the southeast region of Turkey. Afsar CU, Gunaldi M, Kum P, Sahin B, Erkisi M, Kara IO, Paydas S, Duman BB, Ercolak V, Karaca F, Uyeturk U, Guner SI. Asian Pac J Cancer Prev. 2014;15(21):9143-6.

Posters
B1. Helvacı A, Çorbacıoğlu E, Günaldı M, Acute coronary syndrome and its relation with diabetes mellitus and antidiabetic drug, 59th ESCVS International Congress in conjunction with the 6th Congress of Update in Cardiology and Cardiovascular Surgery which will be held in Cesme, Izmir – Turkey on 1 15-18 April 2010. Poster
B2. Meral Gunaldi, Berksoy Sahin, Ufuk Tatlı. Osteonecrosis of the Jaw in patients cancer treated with Bisphosphonates. Mediterranean Multidisciplinary Oncology Forum Congress, 2011
B3. Meral Gunaldi, Ismail Oguz Kara, Cigdem Usul Afsar, Berna Bozkurt Duman. Sorafenib in the treatment of metastatic paraganglioma: A case report. 2012 ASCO Annual Meeting. 1-5 June Chicago/America. J Clin Oncol 30, 2012 (suppl; abstr e13523)
B4. Berna Bozkurt Duman, Meral Gunaldi, Burcak Evren Tasdogan, Cigdem Usul Afsar, Semra Paydas, Yuksel Gumurdulu; Nonalcoholic fatty liver disease after adjuvant therapy in nonmetastatic breast cancer. 2013 ASCO Annual Meeting. 31 May-1 June Chicago/America. J Clin Oncol 31, 2013 (suppl; abstr 9587).
B5. Meral Günaldı, Elif Eda Tiken, Yıldız Okuturlar, Savaş Tuna, Selin Kapan; Neoadjuvant chemotherapy in breast cancer patients: Single centre experience. International Breast Cancer Conference 30 September-02 October, 2014, Istanbul
B6. Elif Eda Tiken, Meral Günaldı, Yıldız Okuturlar, Savaş Tuna; The evalution synchronous bilateral breast cancer patients. International Breast Cancer Conference 30 September-02 October, 2014, Istanbul
B7 . Yıldız Okuturlar, Meral Günaldı, Elif Eda Tiken, Savaş Tuna, Bugra Oztosun, Yesim Inan, Tarik Ercan, Ozlem Harmankaya, Baki Kumbasar; Evaluation of body mass index in breast cancer patients. International Breast Cancer Conference 30 September-02 October, 2014, Istanbul
B8. Meral Gunaldi, Melek Erkisi, Cigdem Usul Afsar, Vehbi Ercolak, Semra Paydas, Ismail Oguz Kara, Berksoy Sahin, Umran Gulec, Ata Secilmis; The evaluation of endometrial thickness and bone mineral density based on CYP2D6 polymorphisims in Turkish breast cancer patients receiving tamoxifen treatment. 2014 ASCO Annual Meeting J Clin Oncol 32, 2014 (suppl; abstr e11559)
B9. C. Usul Afsar, B. Sahin, D. Gumurdulu, E. Kılıc Bagır, R. Burgut, M. Erkisi, O. Kara, M. Gunaldi, V. Ercolak The evaluatıon of fıbroblast growth factor receptor 1 (fgfr1), fıbroblast growth factor 2 (fgf2), phosphatıdylınosıtol 3 phosphate kınase (ıp3k) expressıon and theır clınıcal, prognostıc sıgnıfıcance ın early and advanced stage of squamous cell carcınoma of the lung. 39( th) ESMO Congress (ESMO 2014), Madrid, Spain, 26-30 September, 2014
B10. Y. Okuturlar, A. Gedikbasi, N. Akalin, M. Gunaldi, D. Yilmaz, P. Karakaya, M. Mert, O. Harmankaya; Effects of iron therapy on paraoxonase and arylesterase activities in patients with iron deficiency anemia, IFCC Worldlab Istanbul 2014, 22th International Congress of Clinical Chemistry and Laboratory Medicine, 22-26 June 2014, Istanbul, Turkey

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